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Adults with overweight or obesity newly prescribed liraglutide (Victoza/Saxenda, Novo Nordisk), subcutaneous semaglutide (Ozempic/Wegovy, Novo Nordisk) or tirzepatide (Mounjaro/Zepbound, Eli Lilly) from 2018 to 2023 were included

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For an ingredient to cross it effectively, it typically needs to be small, fat-soluble, and potent at low concentrations (7)